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黄晓红

  • 姓名:黄晓红

    职务:-

    职称:研究员

    联系方式:huangxh@scau.edu.cn

个人简介:

女,博士,教授,博士生导师。广东省现代产业技术体系(淡水鱼)病毒病防控岗位专家。研究方向:海洋鱼类病毒感染致病的细胞及分子机理。 近年来主持完成国家自然科学基金面上项目、863课题、973子课题、国家重点研发计划项目子课题等;在本领域重要国际期刊上发表SCI收录研究论文40多篇;参与申请专利5件,其中授权专利3件;参与编写专著2部。


工作经历:

  

2015.05-2016.05     新加坡国立大学               访问学者

2014.12-至今        中国科学院南海海洋研究所    研究员

2009.10-2014.12     中国科学院南海海洋研究所    副研究员

2009.01-2009.10     中国科学院南海海洋研究所    助理研究员

2006.10-2009.01     中山大学                    博士后



教育经历:

2001.09-2006.07     中国科学院水生生物研究所水生生物学

1997.09-2001.07     河南师范大学淡水渔业


科研项目:

1863课题, 2014AA093507、海水养殖鱼类主要病毒和细菌性病原亚单位疫苗的研发、2014.1-2015.12195、在研、主持。

2.国家自然基金面上项目, 31372566、 石斑鱼泛素蛋白酶体系统对虹彩病毒SGIV感染复制的调节作用机制、2014.1-2017.1278万、在研、主持。

3.国家自然科学基金面上项目,31172445、利用荧光标记重组病毒研究石斑鱼虹彩病毒感染动力学和抗病毒药物筛选、2012.1-2015.1262万、结题、主持。

4973子课题,2012CB114406、鱼类疫病免疫防治的系统疫苗学原理与技术途径、2012.1-2016.1257.1万、结题、主持。


发表论文:

1. Yang   Y, Huang Y, Yu Y, Zhou S, Wang S, Yang M, Qin Q, Huang X*. Negative   regulation of the innate antiviral immune response by TRIM62 from orange   spotted grouper. Fish Shellfish Immunol. 2016, 57:68-78. 

2. Yang Y, Huang Y, Yu Y, Yang M, Zhou S, Qin Q, Huang X*.RING domain is   essential for the antiviral activity of TRIM25 from orange spotted grouper.   Fish Shellfish Immunol. 2016, 55:304-14.

3. Wang W, Huang Y, Yu Y, Yang Y, Xu M, Chen X, Ni S, Qin Q, Huang X*. Fish   TRIM39 regulates cell cycle progression and exerts its antiviral function   against iridovirus and nodavirus. Fish Shellfish Immunol. 2016,50:1-10.

4. Yu Y, Huang Y, Wei S, Li P, Zhou L, Ni S, Huang X**, Qin Q*.A tumour   necrosis factor receptor-like protein encoded by Singapore grouper iridovirus   modulates cell proliferation, apoptosis and viral replication.J Gen Virol.   2016,97(3):756-66.

5. Huang Y, Yu Y, Yang Y, Yang M, Zhou L, Huang X**, Qin Q*. Fish TRIM8   exerts antiviral roles through regulation of the proinflammatory factors and   interferon signaling. Fish Shellfish Immunol. 2016, 54:435-44.

6. Huang Y, Yang M, Yu Y, Yang Y, Zhou L, Huang X**, Qin Q*. Grouper TRIM13   exerts negative regulation of antiviral immune response against nodavirus.   Fish Shellfish Immunol. 2016, 55:106-15.

7. Huang Y, Yu Y, Yang Y, Yang M, Zhou L, Huang X**, Qin Q*. Antiviral   function of grouper MDA5 against iridovirus and nodavirus. Fish Shellfish   Immunol. 2016,54:188-96. 

8. Yu Y, Huang Y, Yang Y, Wang S, Yang M, Huang X**, Qin Q*. Negative   regulation of the antiviral response by grouper LGP2 against fish viruses.   Fish Shellfish Immunol. 2016, 56:358-66.

9. Huang XH, Huang YH, Xu L, Wei SN, Ouyang ZL, Feng J, Qin QW.   Identification and characterizaiton of a novel lymphocystis disease virus   isolate from cultured grouper in China. J Fish Dis. 2015, 38(4):379-87.

10. Huang Y, Ouyang Z, Wang W, Yu Y, Li P, Zhou S, Wei S, Wei J, Huang X**,   Qin Q*. Antiviral role of grouper STING against iridovirus infection. Fish   Shellfish Immunol. 2015, 47(1):157-67.

11. Guo CY, Huang YH, Wei SN, Ouyang ZL, Yan Y, Huang XH**, Qin QW**.   Establishment of a new cell line from the heart of giant grouper, Epinephelus   lanceolatus (Bloch), and its application in toxicology and virus   susceptibility. J Fish Dis. 2015,38(2):175-86

12. Wei S, Huang Y, Huang X**, Qin Q*. Characterization of c-Jun from   orange-spotted grouper, Epinephelus coioides involved in SGIV infection. Fish   Shellfish Immunol. 2015, 43(1):230-40.

13. Huang X, Wang W, Huang Y, Xu L, Qin Q. Involvement of the PI3K and ERK   signaling pathways in largemouth bass virus-induced apoptosis and viral   replication. Fish Shellfish Immunol. 2014,41(2):371-9.

14. Huang X, Huang Y, Yang Y, Wei S, Qin Q. Involvement of fish signal   transducer and activator of transcription 3 (STAT3) in SGIV replication and   virus induced paraptosis. Fish Shellfish Immunol. 2014,41(2):308-16.

15. Wang S#, Huang X##, Huang Y, Hao X, Xu H, Cai M, Wang H, Qin Q.Entry of   a novel marine DNA virus, Singapore grouper iridovirus, into host cells   occurs via clathrin-mediated endocytosis and macropinocytosis in a   pH-dependent manner. J Virol. 2014,88(22):13047-63.

16. Fu J, Huang Y, Cai J, Wei S, Ouyang Z, Ye F, Huang X**, Qin Q*.   Identification and characterization of Rab7 from orange-spotted grouper,   Epinephelus coioides. Fish Shellfish Immunol. 2014, 36(1):19-26.

17. Huang X, Huang Y, Cai J, Wei S, Ouyang Z, Qin Q. Molecular cloning,   expression and functional analysis of ISG15 in orange-spotted grouper,   Epinephelus coioides. Fish Shellfish Immunol. 2013, 34(5):1094-102.

18. Huang X, Huang Y, Cai J, Wei S, Gao R, Qin Q. Identification and   characterization of a tumor necrosis factor receptor like protein encoded by   Singapore grouper iridovirus. Virus Res. 2013,26;178(2):340-8.

19. Huang X, Gong J, Huang Y, Ouyang Z, Wang S, Chen X, Qin Q.   Characterization of an envelope gene VP19 from Singapore grouper iridovirus.   Virology Journal. 2013, 10: 354.

20. Cai J, Huang Y, Wei S, Ouyang Z, Huang X**, Qin Q*. Characterization of   LPS-induced TNFα factor (LITAF) from orange-spotted grouper, Epinephelus   coioides. Fish Shellfish Immunol. 2013, 5(6):1858-66. 

21. Huang XH, Huang YH, Ouyang ZL, Qin QW. Establishment of a cell line   from the brain of grouper (Epinephelus akaara) for cytotoxicity testing and   virus pathogenesis. Aquaculture. 2011, 311:65-73

22. Huang X, Huang Y, Ouyang Z, Xu L, Yan Y, Cui H, Han X, Qin Q. Singapore   grouper iridovirus, a large DNA virus, induces nonapoptotic cell death by a   cell type dependent fashion and evokes ERK signaling. Apoptosis. 2011,   16(8):831-45.

23. Huang X, Huang Y, OuYang Z, Cai J, Yan Y, Qin Q. Roles of   stress-activated protein kinases in the replication of Singapore grouper   iridovirus and regulation of the inflammatory responses in grouper cells. J   Gen Virol. 2011, 92(Pt 6):1292-301.


出版专著和教材:

参与编写 陈松林秦启伟主编《鱼类细胞培养理论与技术》,科学出版社,2011;汪建国主编《鱼病学》,中国农业出版社,2013.